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You’ve Heard of Lactose and Gluten Intolerance.

CSID is characterized by the inability to digest and absorb sugar.1

Congenital Sucrose-Isomaltase Deficiency (CSID) is a rare, inherited disease that causes Sucrose Intolerance.1,2*

Woman laying on her back on the couch, holding her stomach in discomfort with a blanket draped over her legs

*CSID can be referred to as congenital sucrose intolerance, sucrase-isomaltase (SI) deficiency, disaccharide intolerance, or genetic sucrase-isomaltase deficiency (GSID).3,4

Sucrase deficiency—a hallmark of CSID—may be more common than you think.

In a study of 27,875 symptomatic patients

9.3%

had sucrase deficiency.7

CSID Symptoms

CSID symptoms to look for.

CSID symptoms can be commonly mistaken for other GI issues (eg, IBS). You should check for CSID if you think your patients might be experiencing IBS but are not responding to treatment. Symptoms have usually been a problem for a very long time (since childhood or for many years) and may occur more frequently after meals.1,8

Watery Diarrhea

Bloating

Excess Gas Production

Abdominal Cramps

Nausea

Vomiting

What foods contain sucrose?

More than your patients may know. Download our dietary guides to understand what foods may cause issues for your CSID patients.

Download Sucraid® and Your Diet Guide

Testimonials

Hear from patients whose CSID journey led them to Sucraid®.

“[Now] I can eat more and not experience symptoms, so I don’t dislike eating. [CSID] is a disease that can be tested for, and can be managed.”
Stephanie

“

After years of not being heard and starting to believe this was in my head, I now know how to control my symptoms with diet and Sucraid®.

Cheri
“

My son is now able to drink infant formula and eat sucrose-containing foods that would normally cause severe, frequent episodes of diarrhea and weight loss.

Briana
“

After years of not being heard and starting to believe this was in my head, I now know how to control my symptoms with diet and Sucraid®.

Cheri
“

My son is now able to drink infant formula and eat sucrose-containing foods that would normally cause severe, frequent episodes of diarrhea and weight loss.

Briana

These statements reflect individual experiences and should not be used as a substitute for talking with your doctor about whether Sucraid® is right for you. Your doctor can discuss the benefits and risks with you. Each patient experience is unique and QOL Medical, LLC does not provide any warranty or guarantee as to the response a patient will have to Sucraid®.

References
  1. Sucraid® [package insert]. Vero Beach, FL: QOL Medical, LLC; 2024.
  2. Marcadier JL, Boland M, Scott CR, et al. Congenital sucrase-isomaltase deficiency: identification of a common Inuit founder mutation. CMAJ. 2015;187(2):102-7. doi:10.1503/cmaj.140657
  3. MedlinePlus. Congenital sucrase-isomaltase deficiency. Accessed January 6, 2021. https://medlineplus.gov/genetics/condition/congenital-sucrase-isomaltase-deficiency/
  4. QOL Medical, LLC. Is there any difference between congenital sucrase-isomaltase deficiency and genetic sucrase-isomaltase deficiency? Data on file; last updated 2023. sucraid.com/about-csid/csid-vs-gsid/
  5. Puertolas MV, Fifi AC. The role of disaccharidase deficiencies in functional abdominal pain disorders—a narrative review. Nutrients. 2018;10(12):1835. doi:10.3390/nu10121835
  6. Cohen SA. The clinical consequences of sucrase-isomaltase deficiency. Mol Cell Pediatr. 2016;3(1):5. doi:10.1186/s40348-015-0028-0
  7. Nichols BL Jr, Adams B, Roach CM, Ma CX, Baker SS. Frequency of sucrase deficiency in mucosal biopsies. J Pediatr Gastroenterol Nutr. 2012;55(suppl 2):S28-30. doi:10.1097/01.mpg.0000421405.42386.64
  8. Henström M, Diekmann L, Bonfiglio F, et al. Functional variants in the sucrase–isomaltase gene associate with increased risk of irritable bowel syndrome. Gut. 2018;67(2):263–270. doi:10.1136/gutjnl-2016-312456

Important Safety Information for Sucraid® (sacrosidase) Oral Solution

  • Do not prescribe Sucraid® to patients known to be hypersensitive to yeast, yeast products, papain, or glycerin (glycerol).
  • Sucraid® may cause a serious allergic reaction. Patients should stop taking Sucraid® and get emergency help immediately if any of the following side effects occur: difficulty breathing, wheezing, or swelling of the face. Care should be taken when administering initial doses of Sucraid® to observe any signs of acute hypersensitivity reaction.
  • Although Sucraid® provides replacement therapy for the deficient sucrase, it does not provide specific replacement therapy for the deficient isomaltase.
  • Adverse reactions as a result of taking Sucraid® may include worse abdominal pain, vomiting, nausea, diarrhea, constipation, difficulty sleeping, headache, nervousness, and dehydration.
  • Before prescribing Sucraid® to diabetic patients, the physician should consider that Sucraid® will enable sucrose hydrolysis and the absorption of those hydrolysis products, glucose and fructose.
  • The effects of Sucraid® have not been evaluated in patients with secondary (acquired) disaccharidase deficiency.
  • DO NOT HEAT SOLUTIONS CONTAINING SUCRAID®. Do not put Sucraid® in warm or hot fluids. Do not reconstitute or consume Sucraid® with fruit juice since the acidity of the juice may reduce the enzyme activity of Sucraid®. Half of the reconstituted Sucraid® should be taken at the beginning of the meal or snack and the other half during the meal or snack.
  • Sucraid® should be refrigerated at 36°F-46°F (2°C-8°C) and should be protected from heat and light; single-use containers can be removed from refrigeration and stored at 59°F-77°F (15°C-25°C) for up to 3 days (72 hours). Refer to Instructions for Use for full information on how to take Sucraid®.

Indication

Sucraid® (sacrosidase) Oral Solution is indicated for the treatment of sucrase deficiency, which is part of congenital sucrase-isomaltase deficiency (CSID), in adult and pediatric patients 5 months of age and older.

Please see full Prescribing Information.

Sucraid Sacrosidase Oral Solution | HCP Logo See Important Safety Information and Prescribing Information. https://csid.edetail.sucraid.com/#important https://www.sucraidprescribinginformation.com/

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IMPORTANT SAFETY INFORMATION:

Important Safety Information for Sucraid® (sacrosidase) Oral Solution

  • Do not prescribe Sucraid® to patients known to be hypersensitive to yeast, yeast products, papain, or glycerin (glycerol).
  • Sucraid® may cause a serious allergic reaction. Patients should stop taking Sucraid® and get emergency help immediately if any of the following side effects occur: difficulty breathing, wheezing, or swelling of the face. Care should be taken when administering initial doses of Sucraid® to observe any signs of acute hypersensitivity reaction.
  • Although Sucraid® provides replacement therapy for the deficient sucrase, it does not provide specific replacement therapy for the deficient isomaltase.
  • Adverse reactions as a result of taking Sucraid® may include worse abdominal pain, vomiting, nausea, diarrhea, constipation, difficulty sleeping, headache, nervousness, and dehydration.
  • Before prescribing Sucraid® to diabetic patients, the physician should consider that Sucraid® will enable sucrose hydrolysis and the absorption of those hydrolysis products, glucose and fructose.
  • The effects of Sucraid® have not been evaluated in patients with secondary (acquired) disaccharidase deficiency.
  • DO NOT HEAT SOLUTIONS CONTAINING SUCRAID®. Do not put Sucraid® in warm or hot fluids. Do not reconstitute or consume Sucraid® with fruit juice since the acidity of the juice may reduce the enzyme activity of Sucraid®. Half of the reconstituted Sucraid® should be taken at the beginning of the meal or snack and the other half during the meal or snack.
  • Sucraid® should be refrigerated at 36°F-46°F (2°C-8°C) and should be protected from heat and light; single-use containers can be removed from refrigeration and stored at 59°F-77°F (15°C-25°C) for up to 3 days (72 hours). Refer to Instructions for Use for full information on how to take Sucraid®.

Indication

Sucraid® (sacrosidase) Oral Solution is indicated for the treatment of sucrase deficiency, which is part of congenital sucrase-isomaltase deficiency (CSID), in adult and pediatric patients 5 months of age and older.